ICUD/EAU consensus statement on mRCC
The International Consultation on Urological Diseases and the European Association of Urology have published a consensus statement on the management of mRCC (Patard et al. Eur Urol 2011; 60: 684-690; www.ncbi.nlm.nih.gov/pubmed/21704448).
The groups’ recommendations are in accord with other published guidelines. The recommended first-line treatments for patients with a favourable or intermediate prognosis are sunitinib or bevacizumab/interferon-alfa. Temsirolimus is recommended first-line for poor-risk patients. Sunitinib or sorafenib is recommended as second-therapy in patients who have failed prior cytokine therapy.
Newly-added treatment options are pazopanib as a first-line treatment or as second-therapy after prior cytokines. ICUD/EAU now recommends everolimus for second-line treatment in patients who are refractory to VEGF-targeted therapy.
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