Latest Information
June 3, 2015

Patients who have no symptoms at presentation with T3 low-grade tumors and negative lymph nodes experience favorable survival following resection of locally-advanced, non-metastatic renal cell carcinoma (RCC), a recent retrospective study finds.

March 13, 2015

A higher intake by postmenopausal women of lycopene, an antioxidant found in foods like tomatoes, watermelon, and papaya, may lower the risk of renal cell carcinoma, a type of kidney cancer. A study describing these findings was published by Ho et al in Cancer.

February 24, 2015

Neither sorafenib (Nexavar, Bayer HealthCare Pharmaceuticals) nor sunitinib (Sutent, Pfizer Inc), when given in the adjuvant setting, prolong disease-free survival (DFS) in patients with completely resected, locally advanced renal cell carcinoma (RCC) who are at high risk for recurrence, a large phase 3 trial has found.

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Dr. Kevin Zbuk

B.Sc. (Alberta), MD (Alberta), FRCPC

Assistant Professor, McMaster University
Department of Oncology - Division of Medical Oncology


Juravinski Cancer Centre
3rd Floor
699 Concession Street
Hamilton Ontario, L8V 5C2

Contact Information:
P: 905-387-9711 Ext. 64602
F: 905-575-6326

Support Staff:
Karen Chadwick (Administrative Assistant)
P: 905-387-9711 Ext. 64602
F: 905-575-6326

Areas of Interest

Dr. Zbuk's areas of interest include cancer genetics and the molecular classification of gastrointestinal polyposis syndromes. Dr. Zbuk's oncology practice focuses on gastrointestinal malignancies.

Selected Publications

Zbuk K and Eng C “Cancer Phenomics: RET and PTEN as illustrative models”. Nature Reviews Cancer. 2007 Jan;7(1):35-45.

Ni Y*, Zbuk K*, Sadler T, et. al. « Germline mutations and variants in the succinate dehydrogenase genes in Cowden andCowden-like syndromes” American Journal of Human Genetics 2008 (in press)

Plon, S.E., Pirics, M.L., Agrawal, S., Zbuk, K., Nuchtern, J., Hicks, J., Hegde, M., Lip-Hon Chin, E., Eng, C., and H. Russell (2008). Multiple Tumors in a Child with Germline Mutations in TP53 and PTEN. New England J of Medicine, in press.

* joint first authors