April 26, 2012
Two recent studies have reported on the possible utility of assessing pre-treatment neutrophil-to-lymphocyte ratio (NLR) as a prognostic factor in mRCC.
April 26, 2012
A small phase II study of tandutinib (MLN518), a selective inhibitor of type III tyrosine receptor kinases (FLT3), has concluded that the novel agent has no clinical activity and excessive toxicity, and should not be developed further for mRCC.
March 31, 2012
Patients with papillary renal cell carcinoma, the second most common kidney cancer subtype, face a low risk of tumour recurrence and cancer-related death after surgery.
March 29, 2012
Percutaneous image-guided renal mass biopsy (RMB) combined with immunohistochemical (IHC) results can accurately distinguish between benign and malignant tumors, a finding that could help prevent unnecessary nephrectomies, researchers reported at the 37th Annual Scientific Meeting of the Society of Interventional Radiology.
March 26, 2012
Image-guided ablation of primary renal cancers smaller than 4.8 cm may be performed with minimal morbidity and produce excellent results in terms of long-term survival, according to a new study presented at the 37th Annual Scientific Meeting of the Society of Interventional Radiology.
February 14, 2012
Cryotherapy can be used to treat small renal tumors or masses successfully with relatively low rates of complications and recurrence, a urologist skilled in the technique told attendees here at the Renal and Bladder Cancer 3rd National Conference.
February 08, 2012
An immunotherapy (AGS-003) in combination with sunitinib may help prolong the lives of men with unfavorable risk, metastatic renal cell carcinoma (mRCC), according to new data from an open-label phase 2 study.
February 08, 2012
Combining a bisphosphonate with sunitinib may improve progression-free survival (PFS) and overall survival (OS) in patients with bone metastases from renal cell carcinoma (RCC), that are treated with sunitinib, according to a multicenter, retrospective study presented at the 2012 Genitourinary Cancer Symposium.
February 07, 2012
Prior sunitinib treatment for nine months or longer may be associated with a longer progression-free survival (PFS) in patients with metastatic renal cell carcinoma (RCC) receiving axitinib as second-line treatment, according to a new study presented at the 2012 Genitourinary Cancer Symposium
January 30, 2012
In a study of 1,009 patients undergoing partial or radical nephrectomy for unilateral RCC, tumor diameter independently predicted decreased preoperative eGFR after controlling for race and hypertension.
January 27, 2012
The US FDA has approved Inlyta (axitinib) for the treatment of advanced renal cell carcinoma, a type of kidney cancer, in patients with whom other drugs have not been effective, the FDA (Food and Drug Administration) announced today. Inlyta is made and marketed by pharmaceutical giant Pfizer Inc.
January 25, 2012
Higher than normal levels of lead in the blood may signal a risk two times higher than average of developing renal cell carcinoma in smokers, according to medical researchers.
January 11, 2012
In appropriately selected patients, radiofrequency ablation (RFA) is an effective minimally invasive treatment for cT1a renal cell carcinoma (RCC) that offers long-term oncologic outcomes comparable to nephron-sparing surgery, data show.
January 06, 2012
Ultrasound imaging works as well as computed tomography (CT) and magnetic resonance imaging (MRI) for evaluating renal mass size, a new study suggests.
January 4, 2012
“The drug helped patients with advanced renal cell carcinoma live for 11.9 months without their disease progressing in a late-stage study, compared with 9.1 months for those on Nexavar [sorafenib].”
January 02, 2012
Higher blood lead levels are associated with an elevated risk of renal cell carcinoma (RCC), according to a study.
December 28, 2011
Reuters (12/29, Pittman) reports a study in the American Journal of Clinical Nutrition suggesting that people who eat high amounts of red, grilled, or barbequed meat may be at higher risk of kidney cancer. In a study of 500,000 US adults, it was found that eating the most red meat was linked with papillary cancers, but not clear-cell kidney cancers. Participants who ate high amounts of well-done grilled and barbecued meat likewise had an increased risk of kidney cancer. Researchers said the reason for the association is unclear and emphasized that the data do not prove causation.
December 21, 2011
Positive surgical margins (PSMs) are rare in patients undergoing partial nephrectomy (PN) for kidney cancer, researchers found.
December 8, 2011
The International Consultation on Urological Diseases and the European Association of Urology have published a consensus statement on the management of mRCC.
December 8, 2011
Clinical outcomes may be improved in sunitinib-treated mRCC patients who receive concomitant therapy with an angiotensin inhibitor (ACE inhibitor or angiotensin II receptor inhibitor.