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Latest Information
April 26, 2012
Two recent studies have reported on the possible utility of assessing pre-treatment neutrophil-to-lymphocyte ratio (NLR) as a prognostic factor in mRCC.
April 26, 2012
A small phase II study of tandutinib (MLN518), a selective inhibitor of type III tyrosine receptor kinases (FLT3), has concluded that the novel agent has no clinical activity and excessive toxicity, and should not be developed further for mRCC.
March 31, 2012
Patients with papillary renal cell carcinoma, the second most common kidney cancer subtype, face a low risk of tumour recurrence and cancer-related death after surgery.
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Recent Publications

The following list is a selection of recent publications about the management of kidney cancer. Links to the article abstracts and complete articles are provided where available.

Kapoor A. Preferred management option for small renal masses: laparoscopic partial nephrectomy Canadian Urologic Association Journal (CUAJ) 2010 Apr;4(2):139-41
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Kwan KG, Kapoor A. Cytoreductive nephrectomy in metastatic renal cell carcinoma: the evolving role of surgery in the era of molecular targeted therapy. Current Opinion in Support and Palliative Care 2009;3:157-65.
[Abstract]

Kapoor A. Inhibition of mTOR in Kidney Cancer. Current Oncology 2009;16:S33-S39.
[Abstract] | [Full Text]

Klinghoffer Z, Yang B, Kapoor A, Pinthus JH. Obesity and renal cell carcinoma: epidemiology, underlying mechanisms and management considerations. Expert Review of Anticancer Therapy 2009;9:975-87.
[Abstract]

El-Dib R, Touma N, Kapoor A. A Review of the effectiveness and safety of radiofrequency ablation for the treatment of renal tumours. Canadian Urological Association Journal 2009;3:143-9.
[Abstract] | [Full Text]

Kapoor A, Gharajeh A, Sheikh A, Pinthus J. Adjuvant and neoadjuvant small molecule targeted therapy in high-risk renal cell carcinoma. Current Oncology 2009;16:S60-S66.
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Kapoor A, Figlin R. Targeted Inhibition of Mammalian Target of Rapamycin (mTOR) for the Treatment of Advanced Renal Cell Carcinoma. Cancer 2009;115:3618-3630.
[Abstract]

Chatterjee S, Kleinman N, Kapoor A, Whelan JP, Pinthus J. Computerized Tomography Measurement of Visceral Adiposity Predicts Plasma Adiponectin Levels and Metastatic Disease in Patients with Clear Cell Renal Cell Carcinoma. Current Urology 2008;2:188-193.
[Abstract]

Kapoor A. Second Line Treatment for Metastatic Kidney Cancer. Oncology Exchange 2008;27-28.
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Pinthus JH, Tisdale B, Chatterjee S, Lu JP, Hamlet T, Singh G, Farrokhyar F, Kapoor A. Lower plasma adiponectin levels are associated with larger tumor size and metastasis in clear cell carcinoma of the kidney. European Urology 2008;54:866-74.
[Abstract] | [Full Text]

Kapoor A, Tutino R, Kanaroglou A, Hotte S. Treatment of Adult Rhabdoid Renal Cell Carcinoma with Sorafenib. Canadian Urologic Association Journal (CUAJ) 2008;2.
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Hotte SJ, Kapoor A. Systemic Therapy for Patients with Advanced, Unresectable, or Metastatic Renal Cell Carcinoma – Moving to Guidelines. Journal of the Canadian Urologic Association (CUAJ) 2007;1:S35-S40.
[Abstract] | [Full Text]

Kapoor A, Hotte SJ. Current Status of Cytokine Therapy in the Management of Patients with Metastatic Renal Cell Carcinoma. Journal of the Canadian Urologic Association (CUAJ) 2007;1:S28-S33.
[Abstract] | [Full Text]

He L, Fan C, Gillis A, Feng X, Sanatani M, Hotte S, Kapoor A, Tang D. Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma. Biochimica et Biophysica Acta. 2007;1772:1134-42.
[Abstract]

Hudes G, M.D., Carducci M, M.D., Tomczak P, M.D., Dutcher J, M.D., Figlin R, M.D., Kapoor A, M.D. et al. Temsirolimus, Interferon, or the Combination of Interferon plus Temsirolimus for Patients with Advanced Renal Cell Carcinoma and Poor Risk Features. NEW ENGLAND JOURNAL OF MEDICINE 2007;356:2271-81.
[Abstract] | [Full Text]

Kapoor A, Nguan C, Al-Shaiji T, Hussain A, Fazio L, Al-Omar M, Luke PP. Laparoscopic Management of Advanced Renal Cell Carcinoma with Level I Renal Vein Thrombus. UROLOGY 2006;68:514-7.
[Abstract]

Kapoor A, Nassir A, Chew B, Gillis A, Luke PP, Whelan JP. Comparison of Laparoscopic Radical Renal Surgery in the Morbidly Obese and Standard Patients. JOURNAL OF ENDOUROLOGY 2004;18:657-660.
[Abstract]

Beasley K, Omar M, Shaikh A, Bochinski D, Khakhar A, Izawa J, Welsch R, Chin JL, Kapoor A, Luke PP. Laparoscopic vs. Open Partial Nephrectomy. UROLOGY 2004;64:458-61.
[Abstract]

Kapoor A, Zippe C, Gill IS. Emergent Aorto-Renal Revascularization during Retroperitoneal Lymph Node Dissection. JOURNAL OF UROLOGY 1999;162 ;1377-78.